Working With Us

Flexible Solutions, Powerful Results

Rapid, fee-for-service screening against all native kinases in established cell line and tissue panels

• Extensive coverage of both protein kinases and lipid kinases
• Human, rat, and mouse cell line and tissue panels available (KiNativ™ Panels [PDF])
  • Cell Lines: PC3, HL60, Hela, A375, HUH7, Jurkat, A549, MDA231, DU145
  • Human Tissues: PBMC, Heart; Rat Tissues: PBMC, Skin, Brain; MouseTissues: Liver, Muscle, Spleen
  • Additional panels are currently under development

Custom projects in any cell line or tissue, from any species

• Comprehensive coverage of all kinases in your system of interest
• Directly measure on- and off-target potency in your cellular or animal model

Ex vivo profiling of treated cells or animal tissues

• Seamless transition from lysate binding studies to live animal or cell treatments
• Extensive experience with human, dog, rat, and mouse tissues
• Validated methodologies for soluble and membrane proteins
• Virtually no tissue restrictions

Direct binding assay allows interrogation of both type I and type II kinase inhibitors

Comprehensive non-kinase nucleotide binding protein panels also available (heat shock proteins, ABC transporters, etc)

Rapid turn-around (~2 weeks for standard profiling) and cost competitive with recombinant kinase assays

Probes available from Thermo Scientific